Folate Re-standardization effective 1/9/2012
The serum folate assay is standardized to the
World Health Organization (WHO) International
Standard 03/178.
Note new reference range is >=6.0 ng/mL.
Based on comparison studies between the current
and restandardized folate assays, patient samples
will shift upward by approximately 30 to 45%.
The WHO Technical Consultation* on folate and
vitamin B12 deficiencies has determined that
deficient folate concentrations are considered to
be less than 4 ng/mL.
* Food and Nutrition Bulletin. The United Nations
University, 2008:29(2):S238 to 246.